Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780963 | 0.81 | ACLY (0.39) | ALOX15HSD17B10ACLYSMN1; SMN2POLB | |
| SCHEMBL8780958 | 0.79 | ALOX15 (0.35) | ALOX15HSD17B10ACLYSMN1; SMN2POLB | |
| SCHEMBL8662952 | 0.74 | CA2 (0.54) | HSD17B10ACLYSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL24212481 | 0.72 | PIK3C3 (0.47) | HSD17B10 | |
| SCHEMBL30511340 | 0.72 | PIK3C3 (0.47) | HSD17B10 | |
| SCHEMBL8780955 | 0.71 | CA12 (0.36) | ALOX15HSD17B10ACLYCA12CA1 | |
| SCHEMBL8780855 | 0.70 | GAA (0.51) | SMN1; SMN2ALDH1A1MAPTLMNAMAPK1 | |
| SCHEMBL345228 | 0.70 | PDK2 (0.43) | ALOX15HSD17B10ACLYSMN1; SMN2POLB | |
| SCHEMBL23120303 | 0.69 | ALOX15 (0.33) | ALOX15HSD17B10ACLYSMN1; SMN2POLB | |
| SCHEMBL23120284 | 0.68 | ACLY (0.32) | ALOX15HSD17B10ACLYSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790985-A1 | N-ACYL-N-ALKYLAMINO PHENYL SULPHONYL UREAS WITH SULPHUR SUBSTITUENTS, PROCESS FOR THEIR PRODUCTION AND USE AS HERBICIDES AND PLANT GROWTH REGULATORS | Hoechst Schering AgrEvo GmbH (DE) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996014304-A1 | N-ACYL-N-ALKYLAMINO PHENYL SULPHONYL UREAS WITH SULPHUR SUBSTITUENTS, PROCESS FOR THEIR PRODUCTION AND USE AS HERBICIDES AND PLANT GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1996-05-17 | — | — | WO | disclosed |