Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782195 | 0.87 | MRGPRX4 (0.72) | TP53HTTMRGPRX4NPC1FABP4 | |
| SCHEMBL8782218 | 0.84 | MRGPRX4 (0.55) | TP53HTTMRGPRX4NPC1RAB9A | |
| SCHEMBL8783068 | 0.84 | TP53 (0.48) | TP53HTTMRGPRX4HPGDMEN1 | |
| SCHEMBL8782015 | 0.83 | HTT (0.47) | TP53HTTMRGPRX4HPGDNPC1 | |
| SCHEMBL8101220 | 0.83 | RXRA (0.47) | TP53HTTHPGDRXRARXRB | |
| SCHEMBL8782022 | 0.82 | MRGPRX4 (0.53) | TP53HTTMRGPRX4 | |
| SCHEMBL8782065 | 0.82 | TP53 (0.77) | TP53HTTMRGPRX4HPGDRXRA | |
| SCHEMBL2601420 | 0.82 | TP53 (1.00) | TP53HTTMRGPRX4HPGDRXRA | |
| SCHEMBL8782004 | 0.80 | NR4A2 (0.47) | TP53HTTMRGPRX4NPC1KMT2A | |
| SCHEMBL9442060 | 0.80 | RXRA (0.50) | TP53HTTMRGPRX4RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718279-B1 | Process for the preparation of o-substituted benzoylcyanides | BASF AG (DE) | 1997-09-24 | — | — | EP | disclosed |
| EP-0718279-A1 | Process for the preparation of o-substituted benzoylcyanides | BASF AKTIENGESELLSCHAFT (DE) | 1996-06-26 | — | — | EP | disclosed |
| US-5221762-A | Reacting a phenol with benzolactone compound; then phosgene or thionyl chloride; esterification with alcohol | BASF AKTIENGESELLSCHAFT (DE) | 1993-06-22 | — | — | US | disclosed |
| EP-0493711-A1 | Process for the preparation of E-oximethers from phenylglyoxylic acid esters | BASF Aktiengesellschaft (DE) | 1992-07-08 | — | — | EP | disclosed |