Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 11/20 | 0.44 |
| ▸ | MMP2 | P08253 | 4/20 | 0.40 |
| ▸ | MMP9 | P14780 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12472667 | 0.93 | GPR139 (0.44) | GPR139MMP2MMP9POLBMMP3 | |
| SCHEMBL874877 | 0.90 | GPR139 (0.49) | GPR139MMP2MMP9MMP3MMP13 | |
| SCHEMBL877309 | 0.90 | MMP2 (0.51) | GPR139MMP2MMP9POLBMMP3 | |
| SCHEMBL876841 | 0.86 | MMP2 (0.46) | GPR139MMP2MMP9MMP3MMP13 | |
| SCHEMBL877949 | 0.85 | MMP2 (0.46) | GPR139MMP2MMP9MMP3MMP13 | |
| SCHEMBL878111 | 0.84 | MMP2 (0.47) | GPR139MMP2MMP9MMP3MMP13 | |
| SCHEMBL877110 | 0.82 | MMP2 (0.45) | GPR139MMP2MMP9MMP3MMP13 | |
| SCHEMBL875182 | 0.81 | MMP2 (0.51) | GPR139MMP2MMP9MMP3MMP13 | |
| SCHEMBL874990 | 0.80 | MMP2 (0.44) | GPR139MMP2MMP9MMP3MMP13 | |
| SCHEMBL875088 | 0.80 | GPR139 (0.45) | GPR139MMP2MMP9POLBMMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619185-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038942-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |