Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22494209 | 0.77 | AKR1B1 (0.35) | AKR1B1 | |
| SCHEMBL1763273 | 0.75 | AKR1B1 (0.60) | RAPGEF4CA1CA2TSHRMEN1 | |
| SCHEMBL6582497 | 0.72 | MAPT (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL1763070 | 0.72 | RAPGEF4 (0.44) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL2047218 | 0.72 | RAPGEF4 (0.67) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL4735410 | 0.69 | RAPGEF4 (0.44) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL10601772 | 0.69 | RAPGEF4 (0.44) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL5371744 | 0.69 | RAPGEF4 (0.44) | RAPGEF4CA1CA2MMP1MMP2 | |
| SCHEMBL19115314 | 0.68 | LMNA (0.40) | CA1CA2ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL27366442 | 0.68 | SLC40A1 (0.38) | ALDH1A1LMNAL3MBTL1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493925-B1 | Pyrazole derivatives having herbicidal activity, their preparation and their use | SANKYO CO (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5424279-A | Useful for rice crops | SANKYO COMPANY, LIMITED (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0493925-A1 | Pyrazole derivatives having herbicidal activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-07-08 | — | — | EP | disclosed |