Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971606 | 0.88 | MRGPRX4 (0.39) | LMNAKDM4EHPGDMEN1KMT2A | |
| SCHEMBL27674900 | 0.85 | PTK2B (0.41) | KDM4EPTK2BHPGDMEN1KMT2A | |
| SCHEMBL8496813 | 0.84 | PTK2B (0.47) | LMNAKDM4EPTK2BHPGDMEN1 | |
| SCHEMBL8498810 | 0.81 | KMT2A (0.50) | KDM4EPTK2BHPGDMEN1KMT2A | |
| SCHEMBL13505905 | 0.81 | MEN1 (0.50) | KDM4EPTK2BHPGDMEN1KMT2A | |
| SCHEMBL2763295 | 0.81 | PTGDR2 (0.49) | LMNAKDM4EHPGDMEN1KMT2A | |
| SCHEMBL29034766 | 0.81 | KDM4E (0.41) | KDM4EHPGDMEN1KMT2APKM | |
| SCHEMBL8496997 | 0.80 | MEN1 (0.49) | KDM4EPTK2BHPGDMEN1KMT2A | |
| SCHEMBL7049564 | 0.80 | MEN1 (0.49) | KDM4EPTK2BHPGDMEN1KMT2A | |
| SCHEMBL6964590 | 0.80 | ALDH1A1 (0.44) | KDM4EPTK2BHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038975-A2 | PROCESS FOR THE PREPARATION OF (3ARS,12BRS)-5-CHLORO-2-METHYL-2,3,3A12B-TETRAHYDRO-1HDIBENZO[2,3:6,7] OXEPINO [4,5-C]PYRROLE MALEATE AND IT'S PHARMACEUTICAL COMPOSITION THEREOF | MSN LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |