Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 7/20 | 0.43 |
| ▸ | DRD1 | P21728 | 7/20 | 0.43 |
| ▸ | DRD5 | P21918 | 7/20 | 0.43 |
| ▸ | DRD3 | P35462 | 6/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171059 | 0.84 | — | — | |
| SCHEMBL28261421 | 0.82 | ESR2 (0.59) | ESR2HSD17B10TP53TDP1TSHR | |
| Potassium SCHEMBL30562954 | 0.82 | ESR2 (0.59) | ESR2HSD17B10TP53TDP1TSHR | |
| SCHEMBL30991479 | 0.82 | ESR2 (0.59) | ESR2HSD17B10TP53TDP1TSHR | |
| SCHEMBL27457915 | 0.82 | ESR2 (0.59) | ESR2HSD17B10TP53TDP1TSHR | |
| Orthocresol SCHEMBL9854564 | 0.76 | TRPA1 (0.46) | DRD2DRD1DRD5DRD3DRD4 | |
| 2-Phenylphenol SCHEMBL574631 | 0.74 | HPGD (0.57) | ESR2HSD17B10TP53ESR1MEN1 | |
| SCHEMBL31196699 | 0.73 | HTR2A (0.45) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL6905658 | 0.73 | HTR2A (0.45) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL31196698 | 0.73 | HTR2A (0.45) | DRD2DRD1DRD5DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10973935-B2 | Stabilized nanobubbles for diagnostic and therapeutic applications | CASE WESTERN RESERVE UNIVERSITY (US) | 2021-04-13 | — | — | US | disclosed |
| US-20200061220-A1 | STABILIZED NANOBUBBLES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | CASE WESTERN UNIVERSITY | 2020-02-27 | — | — | US | disclosed |
| US-10357575-B2 | Stabilized nanobubbles for diagnostic and therapeutic applications | CASE WESTERN RESERVE UNIVERSITY (US) | 2019-07-23 | — | — | US | disclosed |
| US-20160000824-A1 | TOXICITY ENHANCING COMPOUNDS AND METHODS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-07 | — | — | US | disclosed |
| US-9132149-B2 | Toxicity enhancing compounds and methods | CASE WESTERN RESERVE UNIVERSITY (US) | 2015-09-15 | — | — | US | disclosed |
| US-20140147390-A1 | STABILIZED NANOBUBBLES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2014-05-29 | — | — | US | disclosed |
| US-20120225027-A1 | TOXICITY ENHANCING COMPOUNDS AND METHODS | CASE WESTERN RESERVE UNIVERSITY | 2012-09-06 | — | — | US | disclosed |
| WO-2012040710-A2 | STABILIZED NANOBUBBLES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | CASE WESTERN RESERVE UNIVERSITY (US) | 2012-03-29 | — | — | WO | disclosed |