Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPN | P05981 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorene SCHEMBL2784787 | 0.89 | TRPA1 (0.46) | TRPA1ATMCYP1A2CYP2C19ALDH1A1 | |
| Orthocresol SCHEMBL29395276 | 0.84 | — | — | |
| Orthocresol SCHEMBL8710164 | 0.84 | TRPA1 (0.60) | TRPA1ATMCYP1A2CYP2C19ALDH1A1 | |
| Orthocresol SCHEMBL16002 | 0.84 | — | — | |
| Orthocresol SCHEMBL170162 | 0.84 | TRPA1 (0.60) | TRPA1ATMCYP1A2CYP2C19ALDH1A1 | |
| Orthocresol SCHEMBL10419161 | 0.84 | TRPA1 (0.60) | TRPA1ATMCYP1A2CYP2C19ALDH1A1 | |
| Orthocresol SCHEMBL23093519 | 0.82 | TRPA1 (0.52) | TRPA1ATMCYP1A2CYP2C19ALDH1A1 | |
| Orthocresol SCHEMBL9063647 | 0.82 | TRPA1 (0.52) | TRPA1ATMCYP1A2CYP2C19ALDH1A1 | |
| Orthocresol SCHEMBL11055527 | 0.82 | TRPA1 (0.52) | TRPA1ATMCYP1A2CYP2C19ALDH1A1 | |
| Orthocresol SCHEMBL2210412 | 0.82 | ALDH1A1 (0.62) | TRPA1ATMCYP1A2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418609-A2 | Thermoplastic moulding compositions based on modified polyphenylene ether | HÜLS AKTIENGESELLSCHAFT (DE) | 1991-03-27 | — | — | EP | disclosed |