SCHEMBL8782841

SCHEMBL8782841

CCN(CC)C(=O)n1ccc(S(=O)(=O)c2ccc(C)cc2)n1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
GAA P10253 1/20 0.39
POLB P06746 1/20 0.38
HCRTR2 O43614 3/20 0.38
ALDH1A1 P00352 4/20 0.37
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
AKR1B1 P15121 1/20 0.37
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MCOLN3 Q8TDD5 1/20 0.36
HSP90AA1 P07900 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8783567 0.88 TP53 (0.40) L3MBTL1POLBHCRTR2ALDH1A1LMNA
SCHEMBL8782977 0.88 GAA (0.41) L3MBTL1GAAPOLBALDH1A1HSD17B10
SCHEMBL8782646 0.88 L3MBTL1 (0.38) L3MBTL1POLBALDH1A1HSD17B10AKR1B1
SCHEMBL8782350 0.88 L3MBTL1 (0.38) L3MBTL1POLBALDH1A1LMNAAKR1B1
SCHEMBL8783133 0.88 KMT2A (0.41) TDP1L3MBTL1POLBHCRTR2ALDH1A1
SCHEMBL8783273 0.88 L3MBTL1 (0.49) L3MBTL1GAAPOLBALDH1A1LMNA
SCHEMBL8782760 0.87 ALDH1A1 (0.38) L3MBTL1GAAPOLBHCRTR2ALDH1A1
SCHEMBL8782327 0.86 TSHR (0.41) L3MBTL1GAAPOLBHCRTR2ALDH1A1
SCHEMBL8783829 0.86 ALDH1A1 (0.40) GAAALDH1A1LMNAKMT2AKDM4E
SCHEMBL8783773 0.85 HCRTR2 (0.44) TDP1L3MBTL1GAAHCRTR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0493925-B1 Pyrazole derivatives having herbicidal activity, their preparation and their use SANKYO CO (JP) 1997-11-05 EP disclosed
US-5424279-A Useful for rice crops SANKYO COMPANY, LIMITED (JP) 1995-06-13 US disclosed
EP-0493925-A1 Pyrazole derivatives having herbicidal activity, their preparation and their use Sankyo Company Limited (JP) 1992-07-08 EP disclosed