SCHEMBL8783133

SCHEMBL8783133

CCN(CC)C(=O)n1ccc(S(=O)(=O)c2cc(C)cc(C)c2)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.41
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 2/20 0.41
HTT P42858 2/20 0.36
MAPT P10636 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
HPGD P15428 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
RAPGEF4 Q8WZA2 1/20 0.35
POLB P06746 1/20 0.34
HCRTR2 O43614 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
CPT1A P50416 3/20 0.32
CPT1B Q92523 2/20 0.32
TSPO P30536 2/20 0.32
CPT2 P23786 1/20 0.31
USP2 O75604 1/20 0.31
CRHBP P24387 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8783773 0.89 HCRTR2 (0.44) KMT2AALDH1A1KDM4ETDP1HPGD
SCHEMBL8782841 0.88 TDP1 (0.39) KMT2AALDH1A1KDM4EHTTTDP1
SCHEMBL8782622 0.86 NAMPT (0.36) KMT2AALDH1A1KDM4ETDP1POLB
SCHEMBL8782628 0.86 ALDH1A1 (0.35) KMT2AALDH1A1KDM4EMAPTPOLB
SCHEMBL8783476 0.86 POLB (0.33) KMT2AALDH1A1KDM4ETDP1HPGD
SCHEMBL8783825 0.86 KMT2A (0.48) KMT2AALDH1A1KDM4EMAPTTDP1
SCHEMBL8783829 0.85 ALDH1A1 (0.40) KMT2AALDH1A1KDM4EHTTMAPT
SCHEMBL8783273 0.84 L3MBTL1 (0.49) KMT2AALDH1A1HTTMAPTMEN1
SCHEMBL8782797 0.84 RYR2 (0.39) KMT2AALDH1A1HPGDMEN1LMNA
SCHEMBL8782749 0.82 KMT2A (0.41) KMT2AALDH1A1KDM4EHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0493925-B1 Pyrazole derivatives having herbicidal activity, their preparation and their use SANKYO CO (JP) 1997-11-05 EP disclosed
US-5424279-A Useful for rice crops SANKYO COMPANY, LIMITED (JP) 1995-06-13 US disclosed
EP-0493925-A1 Pyrazole derivatives having herbicidal activity, their preparation and their use Sankyo Company Limited (JP) 1992-07-08 EP disclosed