Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782995 | 1.00 | ALOX5 (0.45) | ALOX5ALDH1A1KLKB1MAPTEPHX2 | |
| SCHEMBL8782867 | 1.00 | ALOX5 (0.45) | ALOX5ALDH1A1KLKB1MAPTEPHX2 | |
| SCHEMBL8783077 | 0.89 | ALOX5 (0.56) | ALOX5ALDH1A1KLKB1MAPT | |
| SCHEMBL8783317 | 0.89 | ALOX5 (0.56) | ALOX5ALDH1A1KLKB1MAPT | |
| SCHEMBL8783087 | 0.89 | ALOX5 (0.56) | ALOX5ALDH1A1KLKB1MAPT | |
| SCHEMBL8783114 | 0.79 | ALOX5 (0.55) | ALOX5ALDH1A1KLKB1MAPTEPHX2 | |
| SCHEMBL8782871 | 0.77 | ALOX5 (0.40) | ALOX5ALDH1A1KLKB1MAPTEPHX2 | |
| SCHEMBL8783000 | 0.77 | ALOX5 (0.40) | ALOX5ALDH1A1KLKB1MAPTEPHX2 | |
| SCHEMBL8942609 | 0.74 | ALOX5 (0.52) | ALOX5ALDH1A1MAPT | |
| SCHEMBL8942314 | 0.74 | ALOX5 (0.41) | ALOX5ALDH1A1KLKB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595995-B1 | ARYLAMIDOALKYL- AND ARYLAMINOALKYL-N-HYDROXYUREA COMPOUNDS AND -N-HYDROXYFORMAMIDE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1997-01-15 | — | — | EP | claimed |
| EP-0595995-B1 | ARYLAMIDOALKYL- AND ARYLAMINOALKYL-N-HYDROXYUREA COMPOUNDS AND -N-HYDROXYFORMAMIDE DERIVATIVES HAVING LIPOXYGENASE INHIBITORY ACTIVITY | ABBOTT LAB (US) | 1997-01-15 | — | — | EP | disclosed |