Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 5/20 | 0.57 |
| ▸ | CA1 | P00915 | 5/20 | 0.57 |
| ▸ | CA2 | P00918 | 5/20 | 0.57 |
| ▸ | CA4 | P22748 | 5/20 | 0.57 |
| ▸ | CA5A | P35218 | 5/20 | 0.57 |
| ▸ | CA7 | P43166 | 5/20 | 0.57 |
| ▸ | CA9 | Q16790 | 5/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27540640 | 0.94 | TDP1 (0.56) | TDP1L3MBTL1CA12CA1CA2 | |
| SCHEMBL27511509 | 0.94 | TDP1 (0.56) | TDP1L3MBTL1CA12CA1CA2 | |
| SCHEMBL11317521 | 0.94 | TDP1 (0.56) | TDP1L3MBTL1CA12CA1CA2 | |
| SCHEMBL11312973 | 0.94 | TDP1 (0.56) | TDP1L3MBTL1CA12CA1CA2 | |
| SCHEMBL20710851 | 0.90 | L3MBTL1 (0.63) | TDP1L3MBTL1CA12CA1CA2 | |
| SCHEMBL777797 | 0.88 | MEN1 (0.56) | CA12CA1CA2CA4CA5A | |
| SCHEMBL28254358 | 0.85 | MEN1 (0.62) | CA12CA1CA2CA4CA5A | |
| SCHEMBL18334409 | 0.83 | MEN1 (0.51) | CA12CA1CA2CA4CA5A | |
| SCHEMBL11818661 | 0.83 | MEN1 (0.51) | MEN1KMT2ALTA4H | |
| SCHEMBL18261836 | 0.83 | MEN1 (0.51) | CA12CA1CA2CA4CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113736075-B | Preparation method of polylactone | 深圳大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-113736075-A | Preparation method of polylactone | 深圳大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-112645978-A | Use of heteropolyacids in the catalytic synthesis of a material compound | 山东卓俊实业有限公司 | 2021-04-13 | — | — | CN | disclosed |
| CN-112625063-A | Preparation method of material compound | 商河知济新材料技术中心 | 2021-04-09 | — | — | CN | disclosed |
| US-10927135-B2 | Metal-free direct arylation of dialkyl phosphonates for the synthesis of mixed alkyl aryl phosphonates | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2021-02-23 | — | — | US | disclosed |
| US-10927135-B2 | Metal-free direct arylation of dialkyl phosphonates for the synthesis of mixed alkyl aryl phosphonates | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2021-02-23 | — | — | US | disclosed |
| US-20200255461-A1 | METAL-FREE DIRECT ARYLATION OF DIALKYL PHOSPHONATES FOR THE SYNTHESIS OF MIXED ALKYL ARYL PHOSPHONATES | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2020-08-13 | — | — | US | disclosed |
| US-20200255461-A1 | METAL-FREE DIRECT ARYLATION OF DIALKYL PHOSPHONATES FOR THE SYNTHESIS OF MIXED ALKYL ARYL PHOSPHONATES | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2020-08-13 | — | — | US | disclosed |
| WO-2019028391-A1 | METAL-FREE DIRECT ARYLATION OF DIALKYL PHOSPHONATES FOR THE SYNTHESIS OF MIXED ALKYL ARYL PHOSPHONATES | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2019-02-07 | — | — | WO | disclosed |
| CN-108291157-A | Selective hydrogenation using flow index | 切弗朗菲利浦化学公司 | 2018-07-17 | — | — | CN | disclosed |
| CN-107107049-A | Selective hydrogenation catalyst and its preparation and application | 切弗朗菲利浦化学公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-102341175-B | Selective hydrogenation catalyst and preparation and application thereof | Chevron Phillips Chemical Co.,L.P. (US) | 2016-11-30 | — | — | CN | disclosed |
| EP-2619213-A1 | MONOHYDROXY CYCLIC PHOSPHONATE SUBSTANTIALLY FREE OF POLYHYDOXY PHOSPHONATE, PROCESS FOR MAKING SAME AND FLAME RETARDANT FLEXIBLE POLYURETHANE FOAM OBTAINED THEREFROM | ICL-IP America Inc. (US) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012040074-A1 | MONOHYDROXY CYCLIC PHOSPHONATE SUBSTANTIALLY FREE OF POLYHYDOXY PHOSPHONATE, PROCESS FOR MAKING SAME AND FLAME RETARDANT FLEXIBLE POLYURETHANE FOAM OBTAINED THEREFROM | ICL-IP AMERICA INC. (US) | 2012-03-29 | — | — | WO | disclosed |
| CN-102341175-A | Selective hydrogenation catalyst and methods of making and using same | CHEVRON PHILLIPS CHEMICAL CO | 2012-02-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255461-A1 | METAL-FREE DIRECT ARYLATION OF DIALKYL PHOSPHONATES FOR THE SYNTHESIS OF MIXED ALKYL ARYL PHOSPHONATES | SLC35B2, PPIP5K2, PPA1 | TDP1 2650/4885L3MBTL1 4127/4885CA12 3108/4885 |
| US-10927135-B2 | Metal-free direct arylation of dialkyl phosphonates for the synthesis of mixed alkyl aryl phosphonates | SLC35B2, PPIP5K2, PPA1 | TDP1 2650/4885L3MBTL1 4127/4885CA12 3108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.