Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783362 | 1.00 | CHRM1 (0.43) | CHRM1MEN1KMT2ACHRM2CHRM5 | |
| SCHEMBL8783996 | 0.87 | CYP2C19 (0.56) | CHRM1MEN1KMT2ACHRM2CHRM5 | |
| SCHEMBL8784000 | 0.87 | CYP2C19 (0.56) | CHRM1MEN1KMT2ACHRM2CHRM5 | |
| SCHEMBL7456380 | 0.82 | CHRM1 (0.44) | CHRM1MEN1KMT2ACHRM2CHRM5 | |
| SCHEMBL7458164 | 0.82 | CHRM1 (0.44) | CHRM1MEN1KMT2ACHRM2CHRM5 | |
| SCHEMBL8760509 | 0.78 | CHRM1 (0.50) | CHRM1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL8797099 | 0.78 | CHRM1 (0.50) | CHRM1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL5389844 | 0.75 | LMNA (0.46) | CHRM1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL5378919 | 0.74 | LMNA (0.45) | MEN1KMT2AKDM4ELMNACYP2C19 | |
| SCHEMBL5375422 | 0.74 | LMNA (0.45) | MEN1KMT2AKDM4ELMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610164-A | (Thiophen-2-yl)-piperidin or tetrahydropyridin azabicyclocarboxamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0755932-A1 | (Thiophen-2-yl)piperidin or tetrahydropyridin-azabicyclocarboxamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-01-29 | — | — | EP | disclosed |