Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784818 | 0.90 | ACHE (0.31) | — | |
| SCHEMBL8783914 | 0.88 | EIF4EBP1 (0.30) | — | |
| SCHEMBL8783284 | 0.86 | KMT2A (0.36) | KMT2A | |
| SCHEMBL9201272 | 0.85 | CYP3A4 (0.33) | KMT2A | |
| SCHEMBL9261159 | 0.84 | EIF4EBP1 (0.32) | KMT2A | |
| SCHEMBL8784205 | 0.83 | NAMPT (0.32) | — | |
| SCHEMBL9209600 | 0.82 | KDM4E (0.31) | KMT2A | |
| SCHEMBL9261164 | 0.80 | EIF4EBP1 (0.33) | KMT2A | |
| SCHEMBL8784371 | 0.79 | EIF4EBP1 (0.31) | KMT2A | |
| SCHEMBL8783765 | 0.78 | KMT2A (0.30) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758328-A1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BTG INTERNATIONAL LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995030673-A1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1995-11-16 | — | — | WO | disclosed |