Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5149419 | 0.80 | — | — | |
| SCHEMBL27628955 | 0.77 | — | — | |
| SCHEMBL790285 | 0.75 | — | — | |
| SCHEMBL1794347 | 0.75 | — | — | |
| SCHEMBL11568413 | 0.74 | TSHR (0.31) | TSHR | |
| SCHEMBL1242860 | 0.73 | L3MBTL1 (0.38) | — | |
| SCHEMBL4307041 | 0.72 | — | — | |
| SCHEMBL1274893 | 0.72 | HIF1A (0.36) | — | |
| SCHEMBL27488043 | 0.72 | KCNQ2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL3873748 | 0.71 | L3MBTL1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0793663-A1 | (THIOPHEN-2-YL)-PIPERIDIN OR TETRAHYDROPYRIDIN CARBOXAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-09-10 | — | — | EP | disclosed |
| US-5610164-A | (Thiophen-2-yl)-piperidin or tetrahydropyridin azabicyclocarboxamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-03-11 | — | — | US | disclosed |
| CN-1142498-A | (Thiophen-2-yl-)-piperidin or tetrahydropyridin azabicyclocarboxamides | AMERICAN HOME PROD (US) | 1997-02-12 | — | — | CN | disclosed |
| EP-0755932-A1 | (Thiophen-2-yl)piperidin or tetrahydropyridin-azabicyclocarboxamides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5525600-A | COMPOUND USEFUL AS ANTIPSYCHOTIC, ANTIDEPRESSANT AND ANXIBLYTIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1996016961-A1 | (THIOPHEN-2-YL)-PIPERIDIN OR TETRAHYDROPYRIDIN CARBOXAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-06-06 | — | — | WO | disclosed |