SCHEMBL1242860

SCHEMBL1242860

NC(=O)ON1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 5/20 0.36
F2 P00734 1/20 0.35
HPGD P15428 3/20 0.34
NPC1 O15118 1/20 0.31
POLB P06746 2/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP9 P14780 1/20 0.31
CA2 P00918 3/20 0.31
CA1 P00915 2/20 0.31
MAPT P10636 2/20 0.30
GAA P10253 1/20 0.30
CHKA P35790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3873748 0.97 L3MBTL1 (0.37) L3MBTL1ALDH1A1F2HPGDNPC1
SCHEMBL1794347 0.97
SCHEMBL790285 0.92
SCHEMBL5149419 0.86
Pyrrolidine SCHEMBL2830893 0.84 CA2 (0.38) ALDH1A1CA2CA1MAPTCHKA
SCHEMBL28062708 0.82 CA2 (0.41) CA2CA1CHKA
SCHEMBL929174 0.80 L3MBTL3 (0.49) L3MBTL1ALDH1A1
SCHEMBL1764108 0.78 CA2 (0.36) CA2CA1MAPTCHKA
SCHEMBL1114107 0.78 ALDH1A1 (0.39) L3MBTL1ALDH1A1HPGDPOLBMMP1
SCHEMBL2483464 0.78 ALDH1A1 (0.39) L3MBTL1ALDH1A1HPGDPOLBMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1189061-B1 Multifunctional erythrocyte reagent containing carbamates and uses IMMUNOTECH SA (FR) 2009-12-02 EP claimed
CN-1894173-A Preparation of 18-fluoro-labeled aromatic amino acids UNIV EBERHARD KARLS (DE) 2007-01-10 CN claimed
CN-1382377-A Operation for onzyme activity of protoporphyrin prooxidase in eukaryotic organism SINGENTA PARTICIPATION AG (CH) 2002-12-04 CN claimed
US-20020115118-A1 Multi-functional reagent for erythrocytes IMMUNOTECH (FR) 2002-08-22 US claimed
WO-1995011895-A1 N-BENZOYL-4-OXY/THIO-2-SUBSTITUTED PIPERIDINES AS SUBSTANCE-P RECEPTOR ANTAGONISTS CIBA-GEIGY AG (CH) 1995-05-04 WO claimed
CN-109476709-B Methods and compositions for conferring and/or enhancing herbicide tolerance using protoporphyrinogen oxidase or variants thereof FARMHANNONG Co.,Ltd. (KR) 2026-05-26 CN disclosed
US-12590123-B2 Compounds and methods for treating cancer, viral infections, and allergic conditions WASHINGTON UNIVERSITY (US) 2026-03-31 US disclosed
EP-3870285-B1 SYNTHESIS OF ESUBERAPROST PRODRUGS UNITED THERAPEUTICS CORP (US) 2025-06-18 EP disclosed
US-20250154181-A1 TREPROSTINIL PRODRUGS UNITED THERAPEUTICS CORPORATION (US) 2025-05-15 US disclosed
CN-119486739-A α4β1/7Integrin ligand conjugated compounds and uses thereof 阿达尔克斯制药有限公司 2025-02-18 CN disclosed
CN-119451678-A Inhibition of histone deacetylase 6 (HDAC 6) 艾科尼佐治疗股份有限公司 2025-02-14 CN disclosed
CN-112566894-B Potent inhibitors of D-amino acid oxidase (DAAO) and uses thereof 心悦生医股份有限公司 2025-01-17 CN disclosed
EP-0844000-A1 Use of alpha, omega-diarylalkane derivatives in the treatment and prevention of psychosis SANKYO COMPANY LIMITED (JP) 1998-05-27 EP disclosed
EP-0790235-A1 Diaryl alkane derivatives containing an alicyclic group, their preparation and their therapeutic and prophylactic uses SANKYO COMPANY LIMITED (JP) 1997-08-20 EP disclosed
CN-1150820-A Manipulation of protoporphyrinogen oxidase enzyme activity in eukaryotes CIBA GEIGY AG (CH) 1997-05-28 CN disclosed
US-5556864-A TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS SANKYO COMPANY, LIMITED (JP) 1996-09-17 US disclosed
EP-0600717-A1 Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis SANKYO COMPANY LIMITED (JP) 1994-06-08 EP disclosed
EP-0026469-B1 DIBENZAZEPINE DERIVATIVES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SANDOZ AG (CH) 1984-11-28 EP disclosed
US-4360525-A NEUROLEPTIC AGENTS, ANTIDEPRESSANTS, SLEEP PROMOTERS SANDOZ LTD. (CH) 1982-11-23 US disclosed
EP-0026469-A1 Dibenzazepine derivatives, their production and pharmaceutical compositions containing them SANDOZ AG (CH) 1981-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154181-A1 TREPROSTINIL PRODRUGS TYMP, TK1, DCTPP1 L3MBTL1 2526/4885ALDH1A1 758/4885F2 1866/4885
US-12590123-B2 Compounds and methods for treating cancer, viral infections, and allergic conditions TMPRSS2, TMPRSS4, F2RL3 L3MBTL1 894/4885ALDH1A1 2827/4885F2 310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.