Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783166 | 0.74 | ABCG2 (0.39) | ALDH1A1ATMABCG2MEN1KMT2A | |
| SCHEMBL8783160 | 0.73 | ABCG2 (0.36) | LMNAPOLBRAB9ATSHRALDH1A1 | |
| SCHEMBL7352477 | 0.72 | ABCG2 (0.41) | POLBSMN1; SMN2RAB9ATSHRALDH1A1 | |
| SCHEMBL21774158 | 0.69 | LMNA (0.47) | LMNASMN1; SMN2TSHRL3MBTL1MAPT | |
| SCHEMBL7352872 | 0.68 | ABCG2 (0.41) | POLBSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL8783164 | 0.68 | TDP1 (0.39) | ALOX5ABCG2MEN1KMT2A | |
| SCHEMBL29438438 | 0.68 | CA12 (0.52) | TSHRALDH1A1 | |
| SCHEMBL1313610 | 0.68 | CA12 (0.52) | TSHRALDH1A1 | |
| SCHEMBL4638150 | 0.68 | AGTR1 (0.45) | POLBSMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL7772856 | 0.68 | MAOB (0.43) | LMNASMN1; SMN2RAB9AL3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760814-A1 | A PROCESS FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1997-03-12 | — | — | EP | disclosed |
| WO-1995032961-A1 | A PROCESS FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1995-12-07 | — | — | WO | disclosed |