Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783262 | 0.90 | MEN1 (0.38) | ABCG2TRPV1CNR1CNR2PKM | |
| SCHEMBL7772783 | 0.85 | FYN (0.43) | ABCG2TRPV1CNR1CNR2PKM | |
| SCHEMBL8783155 | 0.81 | NPSR1 (0.41) | ABCG2TRPV1CNR1CNR2MEN1 | |
| SCHEMBL7774902 | 0.78 | RAB9A (0.50) | PKMHTTMEN1KMT2AUSP2 | |
| SCHEMBL8783164 | 0.76 | TDP1 (0.39) | ABCG2MEN1KMT2ACYP2C9DRD1 | |
| SCHEMBL8784378 | 0.74 | LMNA (0.44) | ABCG2PKMMEN1KMT2AALDH1A1 | |
| SCHEMBL7352477 | 0.73 | ABCG2 (0.41) | ABCG2AGTR1DRD1DRD2DRD4 | |
| SCHEMBL7352872 | 0.71 | ABCG2 (0.41) | ABCG2AGTR1DRD1DRD2DRD4 | |
| SCHEMBL8783160 | 0.71 | ABCG2 (0.36) | ABCG2DRD1DRD2DRD4DRD5 | |
| SCHEMBL4638150 | 0.71 | AGTR1 (0.45) | ABCG2PKMAGTR1DRD1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760814-A1 | A PROCESS FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1997-03-12 | — | — | EP | disclosed |
| WO-1995032961-A1 | A PROCESS FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1995-12-07 | — | — | WO | disclosed |