Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CEL | P19835 | 1/20 | 0.41 |
| ▸ | PPM1D | O15297 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20568006 | 1.00 | KDM4E (0.43) | KDM4EGAAMAPTRAB9AALDH1A1 | |
| SCHEMBL9373695 | 1.00 | KDM4E (0.43) | KDM4EGAAMAPTRAB9AALDH1A1 | |
| SCHEMBL2150813 | 1.00 | KDM4E (0.43) | KDM4EGAAMAPTRAB9AALDH1A1 | |
| SCHEMBL8785374 | 0.98 | KDM4E (0.40) | KDM4EGAAMAPTRAB9AALDH1A1 | |
| SCHEMBL1722278 | 0.90 | CYP3A4 (0.39) | KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL5744913 | 0.85 | CEL (0.39) | KDM4EGAAMAPTRAB9AALDH1A1 | |
| SCHEMBL342395 | 0.82 | HTR1A (0.34) | — | |
| SCHEMBL5793777 | 0.81 | MAPK1 (0.41) | HDAC3HDAC1HDAC2 | |
| SCHEMBL15888532 | 0.81 | SLC6A4 (0.36) | MAPT | |
| SCHEMBL6224719 | 0.78 | RAB9A (0.43) | KDM4EGAAMAPTRAB9ACEL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623113-B1 | PYRAZOLE CARBOXANILIDE FUNGICIDES | MONSANTO CO (US) | 1997-03-05 | — | — | EP | disclosed |
| US-5223526-A | For plants | MONSANTO COMPANY (US) | 1993-06-29 | — | — | US | disclosed |
| WO-1993011117-A1 | PYRAZOLE CARBOXANILIDE FUNGICIDES | MONSANTO COMPANY (US) | 1993-06-10 | — | — | WO | disclosed |