Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.51 |
| ▸ | MIF | P14174 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787461 | 0.87 | NPC1 (0.51) | MAOBNPC1RAB9AALDH1A1GAA | |
| SCHEMBL8788360 | 0.81 | MAOB (0.44) | MAOBNPC1RAB9AMAOAALK | |
| SCHEMBL8787830 | 0.80 | KDM4E (0.50) | MAOBNPC1RAB9AMAOAALDH1A1 | |
| SCHEMBL5921545 | 0.79 | GPR35 (0.56) | MAOBNPC1RAB9AALDH1A1GAA | |
| SCHEMBL7116819 | 0.77 | NPC1 (0.83) | MAOBNPC1RAB9AMAOAALDH1A1 | |
| SCHEMBL5941014 | 0.77 | MIF (0.70) | MAOBNPC1RAB9AMAOAALK | |
| SCHEMBL3148096 | 0.77 | MAOB (0.61) | MAOBNPC1RAB9AMAOAALK | |
| SCHEMBL29427519 | 0.77 | MIF (0.70) | MAOBNPC1RAB9AMAOAALK | |
| SCHEMBL8788290 | 0.77 | MAOB (0.41) | MAOBNPC1RAB9AALDH1A1GAA | |
| SCHEMBL4358139 | 0.75 | NPC1 (1.00) | MAOBNPC1RAB9AMAOAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698575-A | Chromone compounds, pharmaceutical compositions containing the same, and use of the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |