Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MIF | P14174 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788290 | 0.88 | MAOB (0.41) | MAOBNPC1RAB9AMIFKDM4E | |
| SCHEMBL8787000 | 0.81 | MAOB (0.64) | MAOBALKNPC1RAB9AMIF | |
| SCHEMBL8787148 | 0.81 | MAOB (0.33) | MAOB | |
| SCHEMBL8787461 | 0.76 | NPC1 (0.51) | MAOBNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL5921545 | 0.76 | GPR35 (0.56) | MAOBNPC1RAB9AMIFKDM4E | |
| SCHEMBL8786699 | 0.76 | MAOB (0.42) | MAOBNPC1RAB9AKDM4EMAPT | |
| SCHEMBL8787848 | 0.76 | MAOB (0.47) | MAOBALKNPC1RAB9AMIF | |
| SCHEMBL8787946 | 0.74 | RAB9A (0.65) | MAOBNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL15086471 | 0.71 | ALK (0.43) | MAOBALKMIFTP53 | |
| SCHEMBL16674786 | 0.71 | ALK (0.43) | MAOBALKMIFALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698575-A | Chromone compounds, pharmaceutical compositions containing the same, and use of the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |