Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 1.00 |
| ▸ | CASP1 | P29466 | 2/20 | 1.00 |
| ▸ | CASP7 | P55210 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787390 | 0.78 | KDM4E (0.63) | HPGDNPSR1KDM4EHSD17B10CASP1 | |
| SCHEMBL8787226 | 0.77 | HSD17B10 (0.62) | HPGDNPSR1KDM4EHSD17B10CASP1 | |
| SCHEMBL8788264 | 0.76 | MAOB (0.62) | HPGDNPSR1KDM4EHSD17B10CASP1 | |
| SCHEMBL8787173 | 0.75 | KDM4E (0.60) | HPGDNPSR1KDM4EHSD17B10CASP1 | |
| SCHEMBL31046030 | 0.71 | KDM4E (0.55) | HPGDNPSR1KDM4EHSD17B10CASP1 | |
| SCHEMBL8398489 | 0.70 | HPGD (0.63) | HPGDNPSR1KDM4EHSD17B10CASP1 | |
| SCHEMBL5275289 | 0.69 | ALDH1A1 (0.60) | HPGDNPSR1KDM4EHSD17B10CASP1 | |
| SCHEMBL16410893 | 0.68 | RAB9A (0.63) | HPGDNPSR1KDM4EHSD17B10CASP1 | |
| SCHEMBL8787414 | 0.68 | ALDH1A1 (0.53) | HPGDNPSR1KDM4EHSD17B10CASP1 | |
| SCHEMBL12238012 | 0.68 | SMN1; SMN2 (0.63) | HPGDNPSR1KDM4EHSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |