Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268626 | 0.87 | GLA (0.33) | GLALMNA | |
| SCHEMBL8785818 | 0.84 | GLA (0.38) | GLASMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL8785463 | 0.84 | LMNA (0.36) | GLASMN1; SMN2ALDH1A1LMNATP53 | |
| SCHEMBL8786314 | 0.82 | HPGD (0.32) | GLASMN1; SMN2RAB9AHPGD | |
| SCHEMBL8786116 | 0.82 | ALDH1A1 (0.36) | GLASMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL8785232 | 0.80 | CA12 (0.37) | GLASMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL8785677 | 0.79 | GLA (0.39) | GLASMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL8785363 | 0.79 | RAB9A (0.33) | GLASMN1; SMN2RAB9AALDH1A1LMNA | |
| SCHEMBL8786073 | 0.76 | KMT2A (0.42) | SMN1; SMN2RAB9AALDH1A1LMNAHPGD | |
| SCHEMBL8786389 | 0.76 | GLA (0.37) | GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687256-B1 | HYDROXYMETHYL FURAZANE CARBOXYLIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF CARDIO-VASCULAR CONDITIONS | HOECHST AG (DE) | 1997-09-03 | — | — | EP | disclosed |