Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4243701 | 0.81 | ADRA2A (0.46) | ALDH1A1MTORADKNISCHADRA2A | |
| SCHEMBL8787046 | 0.75 | ALDH1A1 (0.54) | ALDH1A1ALOX15MAPK1NPC1TP53 | |
| SCHEMBL8787406 | 0.74 | ALDH1A1 (0.51) | ALDH1A1ALOX15MAPK1NPC1TP53 | |
| SCHEMBL8787938 | 0.73 | ALDH1A1 (0.49) | ALDH1A1ALOX15MAPK1NPC1TP53 | |
| SCHEMBL8788707 | 0.72 | ALDH1A1 (0.50) | ALDH1A1ALOX15MAPK1NPC1TP53 | |
| SCHEMBL1374464 | 0.71 | ALDH1A1 (0.69) | ALDH1A1ALOX15MAPK1NPC1TP53 | |
| SCHEMBL8787468 | 0.70 | ALDH1A1 (0.55) | ALDH1A1ALOX15MAPK1NPC1TP53 | |
| SCHEMBL8788268 | 0.69 | MAPK1 (0.48) | ALDH1A1ALOX15MAPK1NPC1TP53 | |
| SCHEMBL21298288 | 0.69 | ALOX5 (0.44) | ALDH1A1MAPTRAB9AMTORADK | |
| SCHEMBL8788097 | 0.68 | ALDH1A1 (0.47) | ALDH1A1ALOX15MAPK1NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698575-A | Chromone compounds, pharmaceutical compositions containing the same, and use of the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |