Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 4/20 | 0.31 |
| ▸ | USP14 | P54578 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | KHK | P50053 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787038 | 0.86 | DHODH (0.35) | TRPV4CHRM2DHODHPDE4APDE4B | |
| SCHEMBL8786897 | 0.80 | TRPV4 (0.33) | TRPV4ALDH1A1USP14KDM4E | |
| SCHEMBL9138271 | 0.80 | TRPV4 (0.33) | TRPV4ALDH1A1DHODHUSP14KDM4E | |
| SCHEMBL9280355 | 0.78 | DHODH (0.43) | TRPV4ALDH1A1DHODHKDM4E | |
| SCHEMBL6495366 | 0.77 | ALDH1A1 (0.35) | TRPV4ALDH1A1DHODHUSP14 | |
| SCHEMBL20108209 | 0.73 | DHODH (0.43) | DHODH | |
| SCHEMBL29816521 | 0.73 | DHODH (0.43) | DHODH | |
| SCHEMBL6103445 | 0.73 | DHODH (0.42) | TRPV4DHODH | |
| SCHEMBL6729831 | 0.72 | EGLN2 (0.39) | TRPV4ALDH1A1USP14KDM4EPDE4A | |
| SCHEMBL6506928 | 0.72 | TRPV4 (0.36) | TRPV4ALDH1A1USP14KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617026-B1 | Substituted 1-aryltriazolinones | BAYER AG (DE) | 1997-07-30 | — | — | EP | disclosed |
| EP-0617026-A1 | Substituted 1-aryltriazolinones | BAYER AG (DE) | 1994-09-28 | — | — | EP | disclosed |