Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | BCAT2 | O15382 | 7/20 | 0.35 |
| ▸ | BCAT1 | P54687 | 7/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139297 | 0.83 | BCAT2 (0.40) | BCAT2BCAT1ALDH1A1KDM4EHPGD | |
| SCHEMBL9125238 | 0.83 | PGR (0.33) | TRPV4BCAT2BCAT1PGRAR | |
| SCHEMBL6494272 | 0.81 | BCAT2 (0.38) | TRPV4BCAT2BCAT1PGRALDH1A1 | |
| SCHEMBL2526428 | 0.80 | CDK4 (0.38) | BCAT2BCAT1PGRARKDM4E | |
| SCHEMBL6174302 | 0.78 | MEN1 (0.39) | TRPV4BCAT2BCAT1PGRAR | |
| SCHEMBL5844583 | 0.75 | KDM4E (0.40) | TRPV4BCAT2BCAT1AREGLN2 | |
| SCHEMBL20267715 | 0.74 | L3MBTL1 (0.41) | DAOGLA | |
| SCHEMBL6494499 | 0.74 | KDM4E (0.59) | TRPV4ALDH1A1KDM4EGAAUSP14 | |
| SCHEMBL5844322 | 0.72 | CYP11B1 (0.39) | TRPV4BCAT2BCAT1AREGLN2 | |
| SCHEMBL8786897 | 0.72 | TRPV4 (0.33) | TRPV4ALDH1A1KDM4EUSP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6906006-B1 | N-arly-substituted nitrogen-containing heterocycles, processes and novel intermediates for their preparation, and their use as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 2005-06-14 | — | — | US | disclosed |
| US-5554580-A | N-aryl-substituted nitrogen-containing heterocycles intermediates and their use as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-10 | — | — | US | disclosed |
| US-5378681-A | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-03 | — | — | US | disclosed |
| EP-0599135-A1 | Substituted triazolinones | BAYER AG (DE) | 1994-06-01 | — | — | EP | disclosed |
| EP-0370332-B1 | N-aryl-nitrogen heterocycles, process and intermediates for their production and their use as herbicides and in controlling the growth of plants | BAYER AG (DE) | 1994-03-30 | — | — | EP | disclosed |
| US-5006148-A | N-aryl-substituted nitrogen-containing heterocycles, and their use as herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-09 | — | — | US | disclosed |
| EP-0370332-A1 | N-aryl-nitrogen heterocycles, process and intermediates for their production and their use as herbicides and in controlling the growth of plants | BAYER AG (DE) | 1990-05-30 | — | — | EP | disclosed |