Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19153861 | 0.85 | KDM4E (0.50) | CYP2D6KDM4EIDO1LMNAHTR1A | |
| SCHEMBL19597584 | 0.81 | NPC1 (0.42) | CYP2D6KDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL19668457 | 0.79 | SCN4A (0.59) | — | |
| SCHEMBL8181049 | 0.78 | ALDH1A1 (0.44) | LMNAL3MBTL1ALDH1A1CYP1A2NPC1 | |
| SCHEMBL27926709 | 0.78 | LMNA (0.55) | CYP2D6KDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL29359016 | 0.78 | LMNA (0.55) | CYP2D6KDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL10532918 | 0.78 | NPC1 (0.40) | CYP2D6KDM4ELMNAL3MBTL1ALDH1A1 | |
| SCHEMBL5516649 | 0.76 | PTPRA (0.46) | CYP2D6LMNAL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL6491400 | 0.76 | CYP1A2 (0.50) | CYP2D6KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL6491397 | 0.76 | CYP1A2 (0.50) | CYP2D6KDM4ELMNAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587194-B1 | 2-(Heterocycloalkoxy)-1-(subst.-phenyl)-ethanol derivatives as cerebral function improving agents | TOYAMA CHEMICAL CO LTD (JP) | 1997-06-04 | — | — | EP | disclosed |