Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 5/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.48 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.45 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9460653 | 1.00 | CCR3 (0.52) | CCR3CARM1PRMT6MCOLN2MCOLN1 | |
| SCHEMBL14368806 | 0.89 | CCR3 (0.50) | CCR3CARM1PRMT6MCOLN2MCOLN1 | |
| SCHEMBL4429053 | 0.89 | CCR3 (0.50) | CCR3CARM1PRMT6MCOLN2MCOLN1 | |
| SCHEMBL14368967 | 0.86 | KMT2A (0.52) | CCR3ALDH1A1SSTR3POLB | |
| SCHEMBL27757464 | 0.82 | HRH3 (0.52) | ALDH1A1KDM4E | |
| SCHEMBL5662592 | 0.82 | HRH3 (0.52) | ALDH1A1KDM4E | |
| SCHEMBL14368815 | 0.80 | HSD11B1 (0.53) | CCR3ALDH1A1SSTR3 | |
| SCHEMBL14368724 | 0.79 | CCR3 (0.48) | CCR3ALDH1A1 | |
| SCHEMBL27778441 | 0.79 | CCR3 (0.48) | CCR3ALDH1A1 | |
| SCHEMBL13990832 | 0.79 | SSTR3 (0.51) | MCOLN2MCOLN1SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507672-B1 | N-cyclohexyl benzamides derivatives, preparations and therapeutic applications thereof | LOGEAIS LABOR JACQUES (FR) | 1997-06-04 | — | — | EP | disclosed |
| US-5273983-A | 2-Piperidinylmethylcyclohexylaminocarbonyl-substituted benzene | LABORATORIES JACQUES LOGEAIS (FR) | 1993-12-28 | — | — | US | disclosed |
| EP-0507672-A1 | N-cyclohexyl benzamides derivatives, preparations and therapeutic applications thereof | LABORATOIRES JACQUES LOGEAIS Société dite: (FR) | 1992-10-07 | — | — | EP | disclosed |