Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.48 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 3/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29013347 | 0.84 | APP (0.42) | PRKDCPIK3CDPIK3CABRD4 | |
| SCHEMBL8786821 | 0.73 | MAOB (0.42) | ALDH1A1MAPTHPGDTP53CYP1A2 | |
| SCHEMBL8788268 | 0.72 | MAPK1 (0.48) | MAPK1MAPK3MAP2K1ALDH1A1MAPT | |
| SCHEMBL8786795 | 0.72 | HPGD (0.53) | MAPK1MAPK3MAP2K1ALDH1A1MAPT | |
| SCHEMBL8788097 | 0.71 | ALDH1A1 (0.47) | MAPK1MAPK3MAP2K1ALDH1A1MAPT | |
| SCHEMBL30556736 | 0.70 | METAP2 (0.38) | MAPK1MAP2K1ALDH1A1MAPTNPC1 | |
| SCHEMBL31619990 | 0.70 | METAP2 (0.38) | MAPK1MAP2K1ALDH1A1MAPTNPC1 | |
| SCHEMBL15987667 | 0.69 | — | — | |
| SCHEMBL1374464 | 0.69 | ALDH1A1 (0.69) | MAPK1MAPK3MAP2K1ALDH1A1MAPT | |
| SCHEMBL17145024 | 0.68 | BCHE (0.41) | MAPK1ALDH1A1MAPTHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698575-A | Chromone compounds, pharmaceutical compositions containing the same, and use of the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |