Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | TNKS | O95271 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | PARP1 | P09874 | 3/20 | 0.55 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.55 |
| ▸ | GABRP | O00591 | 2/20 | 0.55 |
| ▸ | GABRD | O14764 | 2/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.55 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5092646 | 0.91 | HPGD (0.55) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL8787790 | 0.82 | MAOB (0.50) | SMN1; SMN2CYP1B1CYP1A1MAOBCYP3A4 | |
| SCHEMBL28124980 | 0.77 | MAOB (0.61) | SMN1; SMN2MAOBCA12CA1CA9 | |
| SCHEMBL1423180 | 0.76 | HPGD (0.67) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL4634256 | 0.74 | HPGD (0.73) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL25186939 | 0.73 | HPGD (0.67) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL3205778 | 0.73 | HPGD (0.67) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL2436664 | 0.73 | HPGD (0.67) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL87773 | 0.73 | HPGD (0.67) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 | |
| SCHEMBL8025501 | 0.73 | HPGD (0.67) | HPGDNPC1RAB9ASMN1; SMN2AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698575-A | Chromone compounds, pharmaceutical compositions containing the same, and use of the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |