Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | PRKCB | P05771 | 3/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.49 |
| ▸ | PRKCA | P17252 | 2/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | PRKACG | P22612 | 1/20 | 0.49 |
| ▸ | PRKACB | P22694 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | PRKCH | P24723 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28124984 | 0.86 | MAOB (0.50) | MAOBMAOAPRKCBSIRT2PRKCA | |
| SCHEMBL5396825 | 0.83 | NQO1 (0.67) | MAOBMAOANQO1CA12CA1 | |
| SCHEMBL8787802 | 0.77 | HPGD (0.57) | MAOBCA12CA1CA9MAPK1 | |
| SCHEMBL1202543 | 0.75 | IMPDH2 (0.63) | MAOBPRKCBSIRT2PRKCAPRKD3 | |
| SCHEMBL8788046 | 0.73 | MAOB (0.55) | MAOBMAOAPRKCBSIRT2PRKCA | |
| SCHEMBL31264770 | 0.73 | CA9 (0.68) | MAOBMAOANQO1CA12CA1 | |
| SCHEMBL516275 | 0.73 | CA9 (0.68) | MAOBMAOANQO1CA12CA1 | |
| SCHEMBL28124981 | 0.73 | KDR (0.54) | MAOBNQO1CA12CA1CA9 | |
| SCHEMBL5398907 | 0.72 | NQO1 (0.53) | MAOBMAOANQO1CA12CA1 | |
| SCHEMBL30228412 | 0.72 | KCNA3 (0.62) | MAOANQO1CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106317030-A | 4-indolyl coumarin derivative, and preparing method and application thereof | 国家烟草质量监督检验中心 | 2017-01-11 | — | — | CN | disclosed |
| CN-106317030-A | 4-indolyl coumarin derivative, and preparing method and application thereof | 国家烟草质量监督检验中心 | 2017-01-11 | — | — | CN | disclosed |