Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.38 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | LCAT | P04180 | 2/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788983 | 0.84 | GRIN2B (0.40) | OPRM1SIGMAR1GRIN2BACACBHCRTR1 | |
| SCHEMBL8789012 | 0.76 | GRIN2B (0.37) | OPRM1SIGMAR1GRIN2BACACBHCRTR1 | |
| SCHEMBL8788444 | 0.73 | HRH3 (0.38) | OPRM1SIGMAR1ACACBHRH3HTR1A | |
| SCHEMBL6509757 | 0.71 | MEN1 (0.43) | SIGMAR1 | |
| SCHEMBL8098982 | 0.71 | ALDH1A1 (0.37) | — | |
| SCHEMBL10732284 | 0.70 | L3MBTL1 (0.39) | P2RX7 | |
| SCHEMBL8098675 | 0.70 | NOTUM (0.41) | GRIN2BP2RX7 | |
| SCHEMBL8098667 | 0.70 | HDAC1 (0.38) | — | |
| SCHEMBL9286751 | 0.69 | HRH3 (0.35) | OPRM1SIGMAR1ACACBHRH3HTR1A | |
| SCHEMBL8787984 | 0.69 | HRH3 (0.35) | OPRM1SIGMAR1GRIN2BACACBHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |