Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 14/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788444 | 0.89 | HRH3 (0.38) | HRH3ACACBDRD2DRD3HTR1A | |
| SCHEMBL8787984 | 0.85 | HRH3 (0.35) | HRH3ACACBDRD2DRD3HTR1A | |
| SCHEMBL8105435 | 0.80 | RAB9A (0.37) | — | |
| SCHEMBL8787230 | 0.76 | NTMT1 (0.33) | DRD2DRD3 | |
| SCHEMBL9271854 | 0.74 | DRD2 (0.38) | DRD2DRD3HTR2A | |
| SCHEMBL8789205 | 0.74 | P2RX7 (0.39) | ACACBHTR2AHTR2CHTR2B | |
| SCHEMBL9272668 | 0.72 | CYP17A1 (0.32) | DRD2DRD3 | |
| SCHEMBL8789186 | 0.72 | P2RX7 (0.38) | ACACB | |
| SCHEMBL8788983 | 0.72 | GRIN2B (0.40) | HRH3ACACBDRD2DRD3HTR1A | |
| SCHEMBL8788777 | 0.70 | KDM4E (0.45) | HRH3ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |