Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8786831 | 0.85 | NISCH (0.35) | NISCHGRK2 | |
| SCHEMBL31619990 | 0.75 | METAP2 (0.38) | KDM4EALDH1A1MAPTHSD17B10NPC1 | |
| SCHEMBL30556736 | 0.75 | METAP2 (0.38) | KDM4EALDH1A1MAPTHSD17B10NPC1 | |
| SCHEMBL8786821 | 0.75 | MAOB (0.42) | MAOBMAOAALDH1A1MAPTHPGD | |
| SCHEMBL6316132 | 0.75 | MEN1 (0.39) | MAOBKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8786795 | 0.74 | HPGD (0.53) | CYP19A1KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8787064 | 0.73 | NISCH (0.50) | NISCHMIFMAOBPTPN1MAOA | |
| SCHEMBL11548259 | 0.73 | NISCH (0.50) | NISCHMIFMAOBPTPN1MAOA | |
| SCHEMBL17145024 | 0.73 | BCHE (0.41) | NISCHKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8788009 | 0.72 | GPR35 (0.56) | MAOBMAOAKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698575-A | Chromone compounds, pharmaceutical compositions containing the same, and use of the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |