Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 5/20 | 0.42 |
| ▸ | EDNRB | P24530 | 4/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338352 | 0.77 | EDNRA (0.45) | EDNRAEDNRBAGTR1ALDH1A1KDM4E | |
| SCHEMBL7334516 | 0.74 | EDNRA (0.58) | EDNRAEDNRBAGTR1ALDH1A1TSHR | |
| SCHEMBL7339367 | 0.73 | EDNRA (0.75) | EDNRAEDNRBAGTR1 | |
| SCHEMBL7332362 | 0.69 | EDNRA (0.56) | EDNRAEDNRBAGTR1 | |
| SCHEMBL7337616 | 0.68 | EDNRA (0.43) | EDNRAEDNRBALDH1A1KDM4EMEN1 | |
| SCHEMBL8126633 | 0.67 | EDNRB (0.50) | EDNRAEDNRBALDH1A1KDM4EPKM | |
| SCHEMBL8906313 | 0.67 | EDNRA (0.64) | EDNRAEDNRBAGTR1TSHRMEN1 | |
| SCHEMBL7332065 | 0.66 | EDNRA (0.63) | EDNRAEDNRBAGTR1ALDH1A1TSHR | |
| SCHEMBL7397394 | 0.65 | EDNRA (0.62) | EDNRAEDNRBAGTR1 | |
| SCHEMBL7333106 | 0.64 | PPARG (0.42) | EDNRAEDNRBALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0774965-A4 | PHENOXYPHENYLACETIC ACID DERIVATIVES | MERCK & CO INC (US) | 1997-10-29 | — | — | EP | disclosed |
| EP-0774965-A1 | PHENOXYPHENYLACETIC ACID DERIVATIVES | MERCK & CO. INC. (US) | 1997-05-28 | — | — | EP | disclosed |