Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.60 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | TP53 | P04637 | 8/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | USP2 | O75604 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | CASP1 | P29466 | 4/20 | 0.60 |
| ▸ | BRCA1 | P38398 | 4/20 | 0.60 |
| ▸ | CASP7 | P55210 | 4/20 | 0.60 |
| ▸ | ATM | Q13315 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | HBB | P68871 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787946 | 0.89 | RAB9A (0.65) | MAPTRAB9ATP53NPC1USP2 | |
| SCHEMBL8787165 | 0.83 | RAB9A (0.63) | MAPTRAB9ATP53NPC1USP2 | |
| SCHEMBL8788256 | 0.79 | MAPT (0.70) | MAPTRAB9ATP53NPC1USP2 | |
| SCHEMBL24176810 | 0.76 | RAB9A (0.69) | MAPTRAB9ATP53NPC1USP2 | |
| SCHEMBL8788290 | 0.76 | MAOB (0.41) | MAPTRAB9ATP53NPC1MEN1 | |
| SCHEMBL4583148 | 0.76 | RAB9A (1.00) | MAPTRAB9ATP53NPC1USP2 | |
| SCHEMBL12814273 | 0.75 | RAB9A (0.74) | MAPTRAB9ATP53NPC1USP2 | |
| SCHEMBL20917437 | 0.75 | RAB9A (0.74) | MAPTRAB9ATP53NPC1USP2 | |
| SCHEMBL6329610 | 0.75 | RAB9A (0.74) | MAPTRAB9ATP53NPC1USP2 | |
| SCHEMBL180716 | 0.75 | MAPT (1.00) | MAPTRAB9ATP53NPC1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |