Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.63 |
| ▸ | MAPT | P10636 | 11/20 | 0.63 |
| ▸ | NPC1 | O15118 | 10/20 | 0.63 |
| ▸ | TP53 | P04637 | 7/20 | 0.63 |
| ▸ | ATM | Q13315 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | USP2 | O75604 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | CASP1 | P29466 | 3/20 | 0.63 |
| ▸ | BRCA1 | P38398 | 3/20 | 0.63 |
| ▸ | CASP7 | P55210 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HBB | P68871 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24176810 | 0.89 | RAB9A (0.69) | RAB9AMAPTNPC1TP53ATM | |
| SCHEMBL8788256 | 0.88 | MAPT (0.70) | RAB9AMAPTNPC1TP53ATM | |
| SCHEMBL8788299 | 0.83 | MAPT (0.60) | RAB9AMAPTNPC1TP53ATM | |
| SCHEMBL13609753 | 0.81 | RAB9A (0.55) | RAB9AMAPTNPC1TP53ATM | |
| SCHEMBL8787178 | 0.80 | SMN1; SMN2 (0.49) | RAB9AMAPTNPC1TP53MEN1 | |
| SCHEMBL8787946 | 0.79 | RAB9A (0.65) | RAB9AMAPTNPC1TP53ATM | |
| SCHEMBL8787834 | 0.78 | TNKS (0.46) | RAB9AMAPTNPC1TP53MEN1 | |
| SCHEMBL4583148 | 0.78 | RAB9A (1.00) | RAB9AMAPTNPC1TP53ATM | |
| SCHEMBL12814273 | 0.78 | RAB9A (0.74) | RAB9AMAPTNPC1TP53ATM | |
| SCHEMBL20917437 | 0.78 | RAB9A (0.74) | RAB9AMAPTNPC1TP53ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |