Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ITGAL | P20701 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788351 | 1.00 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1TRPV1RAB9ANPC1 | |
| SCHEMBL14375110 | 0.84 | TRPV1 (0.67) | ALDH1A1L3MBTL1TRPV1RAB9ANPC1 | |
| SCHEMBL20866524 | 0.83 | TRPV1 (0.72) | ALDH1A1L3MBTL1TRPV1RAB9ANPC1 | |
| SCHEMBL2484738 | 0.83 | TRPV1 (0.72) | ALDH1A1L3MBTL1TRPV1RAB9ANPC1 | |
| SCHEMBL8781715 | 0.82 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1TRPV1RAB9ANPC1 | |
| SCHEMBL8781718 | 0.82 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1TRPV1RAB9ANPC1 | |
| SCHEMBL8393112 | 0.81 | ALDH1A1 (0.73) | ALDH1A1L3MBTL1RAB9ANPC1TDP1 | |
| SCHEMBL8393108 | 0.81 | ALDH1A1 (0.73) | ALDH1A1L3MBTL1RAB9ANPC1TDP1 | |
| SCHEMBL25218218 | 0.81 | MAPT (0.62) | ALDH1A1L3MBTL1RAB9ANPC1TDP1 | |
| SCHEMBL25198669 | 0.81 | MAPT (0.62) | ALDH1A1L3MBTL1RAB9ANPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1036064-C | Benzene derivatives having NGF production-promoting activity | SANKYO CO (JP) | 1997-10-08 | — | — | CN | disclosed |
| US-5643925-A | COGNITION ACTIVATORS AND NERVE GROWTH FACTORS | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| US-5614521-A | NERVE GROWTH FACTOR | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0501656-B1 | New benzene derivatives having (NGF) production-promoting activity | SANKYO CO (JP) | 1997-01-22 | — | — | EP | disclosed |
| CN-1064273-A | The new NGF that has generates the active benzene derivative of promotion | SANKYO CO (JP) | 1992-09-09 | — | — | CN | disclosed |
| EP-0501656-A2 | New benzene derivatives having (NGF) production-promoting activity | Sankyo Company Limited (JP) | 1992-09-02 | — | — | EP | disclosed |