SCHEMBL8788362

SCHEMBL8788362

C#CO[Si](C)(C)c1cccc([Si](C)(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8520332 0.79 ESR1 (0.35)
SCHEMBL4572715 0.76 ACHE (0.48) ACHE
SCHEMBL8783588 0.74 ACHE (0.38) ACHE
SCHEMBL4734252 0.69 CA12 (0.41) ACHE
SCHEMBL2959740 0.68 ACHE (0.34) ACHE
SCHEMBL13027843 0.67 ACHE (0.39) ACHE
SCHEMBL18694994 0.66 ACHE (0.41) ACHE
SCHEMBL12818059 0.66 ACHE (0.41) ACHE
SCHEMBL8783948 0.65 CA12 (0.38)
SCHEMBL6274089 0.64 GRM5 (0.42) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0585590-B1 (Alpha, omega) phenylethynyl siloxane monomers, oligomers, and polymers thereof HUGHES AIRCRAFT CO (US) 1997-12-29 EP disclosed
US-5329036-A (alpha, omega)phenylethynyl siloxane monomers, oligomers, and polymers thereof HUGHES AIRCRAFT COMPANY (US) 1994-07-12 US disclosed
EP-0585590-A1 (Alpha, omega) phenylethynyl siloxane monomers, oligomers, and polymers thereof Hughes Aircraft Company (US) 1994-03-09 EP disclosed