Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8791092 | 0.85 | ALDH1A1 (0.46) | ALDH1A1HPGDPOLBMAPTKDM4C | |
| SCHEMBL9845581 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HPGDPOLBMAPTKDM4C | |
| SCHEMBL8791478 | 0.80 | MAPT (0.34) | ALDH1A1POLBMAPT | |
| SCHEMBL8790264 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HPGDPOLBKDM4C | |
| SCHEMBL8792681 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4C | |
| SCHEMBL8947248 | 0.73 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4C | |
| SCHEMBL8791041 | 0.72 | ALDH1A1 (0.49) | ALDH1A1HPGDMAPTKDM4C | |
| SCHEMBL8792333 | 0.71 | ALDH1A1 (0.55) | ALDH1A1HPGDPOLBMAPTKDM4C | |
| SCHEMBL8791414 | 0.71 | ALDH1A1 (0.43) | ALDH1A1HPGDKDM4C | |
| SCHEMBL8947283 | 0.70 | ALDH1A1 (0.57) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421365-B1 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | WAKAMOTO PHARMA CO LTD (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0421365-A2 | Tetrazoleacetic acid derivatives having aldose reductase inhibitory activity | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1991-04-10 | — | — | EP | disclosed |