Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9876777 | 0.90 | CHRM2 (0.34) | CHRM2CHRM1 | |
| SCHEMBL9879920 | 0.83 | CHRM2 (0.37) | CHRM2CHRM1 | |
| SCHEMBL8790855 | 0.80 | HSD11B1 (0.46) | CHRM2 | |
| SCHEMBL8790791 | 0.76 | NR1H4 (0.33) | CHRM2 | |
| SCHEMBL8790767 | 0.76 | HSD11B1 (0.34) | — | |
| SCHEMBL8790669 | 0.74 | CHRM2 (0.36) | CHRM2CHRM1 | |
| SCHEMBL8790031 | 0.74 | HSD11B1 (0.31) | — | |
| SCHEMBL8791005 | 0.73 | CHRM2 (0.38) | CHRM2CHRM1 | |
| SCHEMBL8790019 | 0.73 | — | — | |
| SCHEMBL8790629 | 0.72 | CHRM2 (0.39) | CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413545-B1 | Azabicyclic compounds | BEECHAM GROUP PLC (GB) | 1997-05-14 | — | — | EP | claimed |
| US-5043343-A | Certain 5-substituted-1-aza-bicyclo[3.3.3]heptanes and their pharmaceutical compositions and methods | BEECHAM GROUP P.L.C. (GB) | 1991-08-27 | — | — | US | claimed |
| EP-0413545-A2 | Azabicyclic compounds | Beecham Group p.l.c. (GB) | 1991-02-20 | — | — | EP | claimed |
| JP-3086883-A | — | — | None | — | — | JP | disclosed |
| EP-0413545-B1 | Azabicyclic compounds | BEECHAM GROUP PLC (GB) | 1997-05-14 | — | — | EP | disclosed |
| US-5157160-A | Treatment of diseases of the nervous system | BEECHAM GROUP P.L.C. (GB) | 1992-10-20 | — | — | US | disclosed |
| JP-H0386883-A | NEW COMPOUND, PREPARATION OF IT AND COMPOSITION OF DRUG CONTAINING IT | BEECHAM GROUP PLC | 1991-04-11 | — | — | JP | disclosed |