SCHEMBL9879920

SCHEMBL9879920

Nc1noc(C23CCN(CC2)C3)n1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.37
CHRM1 P11229 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9876777 0.94 CHRM2 (0.34) CHRM2CHRM1
SCHEMBL8790214 0.83 CHRM2 (0.33) CHRM2CHRM1
SCHEMBL9049262 0.79 CHRM2 (0.48) CHRM2
SCHEMBL8872958 0.69 CHRM1 (0.50) CHRM2CHRM1
SCHEMBL9699382 0.68 CHRM2 (0.32) CHRM2CHRM1
SCHEMBL9139968 0.64
SCHEMBL9049720 0.62 PDK2 (0.34)
SCHEMBL6981603 0.60
SCHEMBL8790791 0.59 NR1H4 (0.33) CHRM2
SCHEMBL9293589 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4988706-A Treatment of dementia in mammals, central nervous system disorders, cognition activators BEECHAM GROUP P.L.C. (GB) 1991-01-29 US disclosed