Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8791007 | 0.92 | NR1H4 (0.36) | NR1H4NR1I2CYP2C9CYP2C19 | |
| SCHEMBL8790855 | 0.76 | HSD11B1 (0.46) | HSD11B1CHRM2 | |
| SCHEMBL8790214 | 0.76 | CHRM2 (0.33) | CHRM2 | |
| SCHEMBL8790767 | 0.73 | HSD11B1 (0.34) | HSD11B1 | |
| SCHEMBL22352913 | 0.71 | NR1H4 (0.41) | NR1H4NR1I2CYP2C9CYP2C19 | |
| SCHEMBL8790669 | 0.71 | CHRM2 (0.36) | HSD11B1CHRM2 | |
| SCHEMBL9049643 | 0.70 | HSD11B1 (0.46) | HSD11B1CHRM2 | |
| SCHEMBL8790019 | 0.70 | — | — | |
| SCHEMBL8791005 | 0.70 | CHRM2 (0.38) | HSD11B1CHRM2 | |
| SCHEMBL22347352 | 0.69 | NR1H4 (0.43) | NR1H4NR1I2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413545-B1 | Azabicyclic compounds | BEECHAM GROUP PLC (GB) | 1997-05-14 | — | — | EP | claimed |
| EP-0413545-A2 | Azabicyclic compounds | Beecham Group p.l.c. (GB) | 1991-02-20 | — | — | EP | claimed |