Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844853 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2HTTKMT2ATDP1ALDH1A1 | |
| SCHEMBL18191920 | 0.93 | ALDH1A1 (0.46) | SMN1; SMN2KMT2AALDH1A1ADRB2ADRB1 | |
| SCHEMBL812745 | 0.93 | ALDH1A1 (0.46) | SMN1; SMN2KMT2AALDH1A1ADRB2ADRB1 | |
| SCHEMBL7637417 | 0.93 | ALDH1A1 (0.46) | SMN1; SMN2KMT2AALDH1A1ADRB2ADRB1 | |
| SCHEMBL18191935 | 0.93 | ALDH1A1 (0.46) | SMN1; SMN2KMT2AALDH1A1ADRB2ADRB1 | |
| SCHEMBL879299 | 0.91 | ALDH1A1 (0.39) | SMN1; SMN2HTTALDH1A1TP53TSHR | |
| SCHEMBL3972242 | 0.91 | ALDH1A1 (0.39) | SMN1; SMN2HTTALDH1A1TP53TSHR | |
| SCHEMBL4441643 | 0.91 | SMN1; SMN2 (0.45) | SMN1; SMN2HTTKMT2ATDP1ALDH1A1 | |
| SCHEMBL845063 | 0.90 | ALDH1A1 (0.38) | SMN1; SMN2HTTKMT2ATDP1ALDH1A1 | |
| SCHEMBL16368817 | 0.90 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1ATMADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7074828-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2006-07-11 | — | — | US | claimed |
| EP-1868982-B1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | UNIV ALBERTA (CA) | 2015-04-29 | — | — | EP | disclosed |
| US-8202901-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-06-19 | — | — | US | disclosed |
| US-8202901-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-06-19 | — | — | US | disclosed |
| EP-1499580-B1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | UNIV ALBERTA (CA) | 2012-03-28 | — | — | EP | disclosed |
| US-20090258835-A1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA TEC EDMONTON (CA) | 2009-10-15 | — | — | US | disclosed |
| US-20090258835-A1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA TEC EDMONTON (CA) | 2009-10-15 | — | — | US | disclosed |
| US-7524885-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-04-28 | — | — | US | disclosed |
| US-7524885-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-04-28 | — | — | US | disclosed |
| US-7524885-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-04-28 | — | — | US | disclosed |
| US-7473706-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-01-06 | — | — | US | disclosed |
| US-7473706-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-01-06 | — | — | US | disclosed |
| US-7473706-B2 | Compounds that stimulate glucose utilization and methods of use | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2009-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258835-A1 | COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE | GPR119, SLC2A4, SLC2A1 | SMN1; SMN2 3712/4885HTT 4544/4885KMT2A 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.