SCHEMBL879299

SCHEMBL879299

O=C(OCCOCCOCCOC(=O)C1CC1)C1CC1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
TSHR P16473 3/20 0.39
TP53 P04637 2/20 0.39
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPT P10636 3/20 0.36
PPM1B O75688 1/20 0.35
PTPN1 P18031 1/20 0.35
PPP1CC P36873 1/20 0.35
HPGD P15428 1/20 0.33
RAB9A P51151 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
NPC1 O15118 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3972242 1.00 ALDH1A1 (0.39) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL207843 0.92 MAPT (0.39) ALDH1A1MAPTPPM1BPTPN1PPP1CC
SCHEMBL16368839 0.91 LMNA (0.42) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL17085312 0.91 LMNA (0.42) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL844853 0.91 SMN1; SMN2 (0.42) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL879035 0.91 SMN1; SMN2 (0.42) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL845076 0.89 ALDH1A1 (0.38) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL17085305 0.89 ALDH1A1 (0.38) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL16368824 0.89 GAA (0.44) ALDH1A1TP53PPM1BPTPN1PPP1CC
SCHEMBL5656419 0.89 ALDH1A1 (0.52) ALDH1A1TSHRMAPTPPM1BPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150188193-A1 NON-AQUEOUS LIQUID ELECTROLYTE FOR SECONDARY BATTERY AND SECONDARY BATTERY FUJIFILM CORPORATION (JP) 2015-07-02 US disclosed
EP-1868982-B1 COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE UNIV ALBERTA (CA) 2015-04-29 EP disclosed
US-8202901-B2 Compounds that stimulate glucose utilization and methods of use THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2012-06-19 US disclosed
US-8202901-B2 Compounds that stimulate glucose utilization and methods of use THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2012-06-19 US disclosed
EP-1499580-B1 COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE UNIV ALBERTA (CA) 2012-03-28 EP disclosed
US-20090258835-A1 COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE THE GOVERNORS OF THE UNIVERSITY OF ALBERTA TEC EDMONTON (CA) 2009-10-15 US disclosed
US-20090258835-A1 COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE THE GOVERNORS OF THE UNIVERSITY OF ALBERTA TEC EDMONTON (CA) 2009-10-15 US disclosed
US-7524885-B2 Compounds that stimulate glucose utilization and methods of use THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2009-04-28 US disclosed
US-7524885-B2 Compounds that stimulate glucose utilization and methods of use THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2009-04-28 US disclosed
US-7473706-B2 Compounds that stimulate glucose utilization and methods of use THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2009-01-06 US disclosed
US-7473706-B2 Compounds that stimulate glucose utilization and methods of use THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2009-01-06 US disclosed
US-7473706-B2 Compounds that stimulate glucose utilization and methods of use THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2009-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090258835-A1 COMPOUNDS THAT STIMULATE GLUCOSE UTILIZATION AND METHODS OF USE GPR119, SLC2A4, SLC2A1 ALDH1A1 1918/4885TSHR 623/4885TP53 4505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.