Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.49 |
| ▸ | PRCP | P42785 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717581 | 0.92 | PRCP (0.50) | OPRM1PRCPALDH1A1SLC22A1KDM4E | |
| SCHEMBL8789518 | 0.92 | PRCP (0.50) | OPRM1PRCPALDH1A1SLC22A1KDM4E | |
| SCHEMBL3453173 | 0.85 | OPRM1 (0.56) | OPRM1PRCPALDH1A1SLC22A1KDM4E | |
| SCHEMBL330238 | 0.84 | OPRM1 (0.57) | OPRM1PRCPALDH1A1SLC22A1KDM4E | |
| SCHEMBL329925 | 0.84 | OPRM1 (0.57) | OPRM1PRCPALDH1A1SLC22A1KDM4E | |
| SCHEMBL329828 | 0.84 | OPRM1 (0.57) | OPRM1PRCPALDH1A1SLC22A1KDM4E | |
| SCHEMBL9373834 | 0.80 | PRCP (0.51) | OPRM1PRCPALDH1A1SLC22A1KDM4E | |
| SCHEMBL9373828 | 0.80 | PRCP (0.51) | OPRM1PRCPALDH1A1SLC22A1KDM4E | |
| SCHEMBL9373842 | 0.80 | PRCP (0.51) | OPRM1PRCPALDH1A1SLC22A1KDM4E | |
| SCHEMBL9423819 | 0.76 | PRCP (0.56) | OPRM1PRCPALDH1A1SLC22A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501997-B1 | N-ACYL-SUBSTITUTED AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS PHARMACEUTICALS | SMITHKLINE BEECHAM SPA (IT) | 1997-01-29 | — | — | EP | disclosed |
| EP-0501997-A1 | N-ACYL-SUBSTITUTED AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS PHARMACEUTICALS. | ZAMBELETTI SPA L (IT) | 1992-09-09 | — | — | EP | disclosed |
| WO-1991008206-A1 | N-ACYL-SUBSTITUTED AZACYCLIC COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS PHARMACEUTICALS | DR. LO. ZAMBELETTI S.P.A. (IT) | 1991-06-13 | — | — | WO | disclosed |