Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658885 | 0.76 | SLC6A4 (0.56) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| SCHEMBL11613799 | 0.76 | ALDH1A1 (0.52) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| SCHEMBL10179843 | 0.76 | CA1 (0.39) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| SCHEMBL28446506 | 0.74 | IDO1 (0.46) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| SCHEMBL28444880 | 0.74 | IDO1 (0.46) | — | |
| SCHEMBL28438760 | 0.74 | TAAR1 (0.42) | HTR2A | |
| SCHEMBL3034699 | 0.74 | ESR1 (0.58) | SLC6A2ESR1 | |
| SCHEMBL1610148 | 0.74 | ESR1 (0.58) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| SCHEMBL3034697 | 0.74 | SLC6A2 (0.33) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| SCHEMBL1119582 | 0.74 | ESR1 (0.31) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639776-A | CROP PESTICIDE; NONPHYTOTOXIC, KIDNEY BEANS, ORANGES | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0751130-A1 | 4,5-DIHYDROPYRAZOLE-5-THIONE DERIVATIVES AND ACARICIDE CONTAINING THE SAME | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-01-02 | — | — | EP | disclosed |