Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398164 | 0.85 | BCAT2 (0.48) | HNF4ABCAT2CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL6832583 | 0.78 | BCAT2 (0.50) | HNF4APLAUPLATBCAT2ALDH1A1 | |
| SCHEMBL5010723 | 0.77 | HNF4A (0.53) | HNF4ABCAT2CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL225203 | 0.73 | HNF4A (0.71) | HNF4ABCAT2CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL5010126 | 0.73 | HNF4A (0.50) | HNF4ABCAT2CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL8778491 | 0.73 | HNF4A (0.60) | HNF4APLAUPLATBCAT2CHRNB2 | |
| SCHEMBL5008857 | 0.72 | HNF4A (0.48) | HNF4APLAUPLATBCAT2CHRNB2 | |
| SCHEMBL5010686 | 0.72 | HNF4A (0.48) | HNF4APLAUPLATBCAT2CHRNB2 | |
| SCHEMBL7367739 | 0.71 | BCAT2 (0.35) | BCAT2CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL16113000 | 0.71 | HNF4A (0.44) | HNF4ABCAT2CHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801649-A2 | HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE MOLECULAR CHAPERON PRODUCTION AND THE PREPARATION THEREOF | BIOREX KUTATO ES FEJLESZTÖ RT. (HU) | 1997-10-22 | — | — | EP | disclosed |
| WO-1997016439-A1 | HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE MOLECULAR CHAPERON PRODUCTION AND THE PREPARATION THEREOF | Biorex Kutató és Fejlesztó Rt. (HU) | 1997-05-09 | — | — | WO | disclosed |