Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523645 | 0.77 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8790867 | 0.70 | CHRM2 (0.35) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8557075 | 0.69 | CHRM2 (0.46) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8790912 | 0.69 | CHRM2 (0.34) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9052128 | 0.68 | CHRM2 (0.45) | CHRM2CHRM4CHRM1CHRM3 | |
| Oxalic Acid SCHEMBL8791271 | 0.68 | CHRM2 (0.39) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL19271801 | 0.67 | GLA (0.32) | — | |
| SCHEMBL9050408 | 0.67 | CHRM2 (0.38) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7499126 | 0.67 | CHRM2 (0.37) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL9845828 | 0.67 | CHRM2 (0.32) | CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413545-B1 | Azabicyclic compounds | BEECHAM GROUP PLC (GB) | 1997-05-14 | — | — | EP | claimed |
| EP-0413545-A2 | Azabicyclic compounds | Beecham Group p.l.c. (GB) | 1991-02-20 | — | — | EP | claimed |
| EP-0413545-B1 | Azabicyclic compounds | BEECHAM GROUP PLC (GB) | 1997-05-14 | — | — | EP | disclosed |
| US-5157160-A | Treatment of diseases of the nervous system | BEECHAM GROUP P.L.C. (GB) | 1992-10-20 | — | — | US | disclosed |
| US-5043343-A | Certain 5-substituted-1-aza-bicyclo[3.3.3]heptanes and their pharmaceutical compositions and methods | BEECHAM GROUP P.L.C. (GB) | 1991-08-27 | — | — | US | disclosed |
| EP-0413545-A2 | Azabicyclic compounds | Beecham Group p.l.c. (GB) | 1991-02-20 | — | — | EP | disclosed |