SCHEMBL9845828

SCHEMBL9845828

CC(=O)N(N)C(=O)C12CCCN(C1)C2

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8523645 0.75 CHRM2 (0.38) CHRM2CHRM4CHRM1CHRM3
SCHEMBL8790912 0.71 CHRM2 (0.34) CHRM2CHRM4CHRM1CHRM3
SCHEMBL8790867 0.69 CHRM2 (0.35) CHRM2CHRM4CHRM1CHRM3
SCHEMBL8557075 0.68 CHRM2 (0.46) CHRM2CHRM4CHRM1CHRM3
SCHEMBL9458387 0.67 CHRM2 (0.38) CHRM2CHRM4CHRM1CHRM3
SCHEMBL8790010 0.67 CHRM2 (0.41) CHRM2CHRM4CHRM1CHRM3
SCHEMBL8790499 0.67 CHRM2 (0.33) CHRM2CHRM4CHRM1CHRM3
SCHEMBL3951763 0.65 CHRM2 (0.39) CHRM2CHRM4CHRM1CHRM3
SCHEMBL9049033 0.64 CHRM2 (0.42) CHRM2CHRM4CHRM1CHRM3
SCHEMBL6626696 0.63 CHRM2 (0.49) CHRM2CHRM4CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413545-A2 Azabicyclic compounds Beecham Group p.l.c. (GB) 1991-02-20 EP claimed