Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.44 |
| ▸ | MMP8 | P22894 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | BRS3 | P32247 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790623 | 1.00 | MMP2 (0.44) | MMP2MMP9MMP8GAAMAPT | |
| SCHEMBL8789119 | 0.94 | MAPT (0.44) | MMP2MMP9MMP8GAAMAPT | |
| SCHEMBL8790279 | 0.89 | MAPT (0.46) | MMP2MMP9MMP8GAAMAPT | |
| SCHEMBL9421662 | 0.88 | MMP2 (0.49) | MMP2MMP9MMP8GAAMAPT | |
| SCHEMBL9421665 | 0.88 | MMP2 (0.49) | MMP2MMP9MMP8GAAMAPT | |
| SCHEMBL6491342 | 0.85 | GHSR (0.53) | MMP2MMP9MMP8GAAMAPT | |
| SCHEMBL8792189 | 0.85 | GHSR (0.53) | MMP2MMP9MMP8GAAMAPT | |
| SCHEMBL9421664 | 0.84 | TACR1 (0.47) | MMP2MMP9MMP8GAAMAPT | |
| SCHEMBL9421668 | 0.84 | TACR1 (0.47) | MMP2MMP9MMP8GAAMAPT | |
| SCHEMBL8790284 | 0.84 | PSMB5 (0.39) | MMP9MMP8MMP1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994011012-A1 | SUBSTITUTED DIPEPTIDE ANALOGS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1994-05-26 | — | — | WO | claimed |
| EP-0669830-A4 | SUBSTITUTED DIPEPTIDE ANALOGS PROMOTE RELEASE OF GROWTH HORMONE. | MERCK & CO INC (US) | 1997-02-26 | — | — | EP | disclosed |
| EP-0669830-A1 | SUBSTITUTED DIPEPTIDE ANALOGS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO. INC. (US) | 1995-09-06 | — | — | EP | disclosed |
| WO-1994011012-A1 | SUBSTITUTED DIPEPTIDE ANALOGS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1994-05-26 | — | — | WO | disclosed |